Abstract :Ectodermal dysplasia (ED) is an inherited disorder characterized by the abnormal development of ectodermally derived anatomic structures, with features such as onchodysplasia, trichodysplasia, dyshidrosis, and oligodontia. Hypoplasia of the alveolar ridges is also associated and removable prosthodontics is the most common treatment modality for dental management. Oral rehabilitation is recommended for the positive development of self-esteem as well as for improved speech, masticatory function and facial esthetics. The purpose of this article is to present early prosthetic rehabilitation of two toddlers or very young patients with ED, aiming to contribute to enhance the current literature, considering that it does not provide much information on this topic.